If you’ve been cutting calories, prioritizing protein over carbs, and taking daily walks… 

But still don’t see a change on the scale…

Chances are you’re frustrated. 

But thanks to breakthrough research, we now know it’s not your age or genetics… 

But instead, a little-known “weight loss hormone” that declines over time and could be the key to finally shedding that stubborn weight!

A Harvard researcher was awarded the prestigious 2024 Lasker DeBakey Clinical Medical Research Award for discovering this “weight loss hormone…”

And since then, it’s taken the weight loss industry by storm. 

Many people have even turned to artificial forms of this hormone to minimize appetite and effortlessly burn fat… 

But as with anything artificial, it comes with a lengthy list of negative side effects.

And experts recommend anyone over 65 avoid this chemical solution!

But here’s the good news…

Research published in 2023 discovered one botanical that can help activate your body’s production of the “weight loss hormone” naturally!

And the results are astounding… 

Simply activating this hormone is scientifically backed to help…

And because it’s natural, you don’t have to worry about the scary side-effects or high price point associated with the trendy, artificial treatment!

This natural botanical has been shown to be so powerful that some review studies have found supplementing with it was associated with significant reductions in body weight, body mass index, and waist size.

And it works by activating a naturally occurring weight loss hormone called glucagon-like peptide, or GLP-1.

GLP-1 is responsible for supporting healthy blood sugar, regulating metabolism, and controlling appetite.

If your levels of this hormone are low, losing weight is an uphill battle.

That’s where this little-known botanical comes in.

By activating your body’s natural production of GLP-1, you can finally start seeing the results you’ve been working so hard to achieve. 

But there’s one catch…

If your body doesn’t already have low levels of GLP-1, it might not work for you. 

So, before revealing the scientifically backed benefits of this incredible weight loss botanical and how you can use it to finally shed that stubborn weight, let’s take a look at…

As weight loss treatments using the GLP-1 hormone were rising in popularity, there was little research on how age affects the body’s levels of this hormone.

Until 2023, when researchers took tissue samples from the digestive systems of people aged 27-93.

They found a significant decline in GLP-1 levels in older individuals, with the drop-off beginning around age 40!

So, if you’re 40 or older, chances are your body’s production of this weight loss hormone is steadily dropping, which could be a major cause of belly fat and stubborn weight that you just can’t lose. 

Because GLP-1 is essential for regulating blood sugar, low levels could mean you’re constantly riding a blood sugar rollercoaster!

When your blood sugar levels are in peaks and valleys all day long, your cravings go haywire.

And when it drops to those valleys, your body goes into panic mode, desperate to get your blood sugar levels back up. 

The easiest way to do that? Eating carbs & sugar. 

Now, if you’re actively trying to lose weight, chances are you’re very in tune with your cravings.

And if you feel like you have a sweet tooth every night after dinner… 

Or all you want for lunch is a hearty sandwich or a big, doughy piece of bread… 

You could have unhealthy blood sugar caused by low levels of GLP-1.

GLP-1 is also one of the major drivers of appetite.

It works in two ways:

1. Slowing the rate at which food leaves your stomach, so you feel fuller for longer. 
2. Activating neural pathways in the brain that trigger satiety, or the feeling of being full. 

So if you notice you’re scouring the pantry for a snack within an hour of eating a meal…

It could be that your body didn’t have enough GLP-1 to slow down the food from leaving your stomach… 

Or to alert your brain that you are full! 

If any of this sounds familiar, there’s a good chance your weight loss struggles are a result of low levels of this weight loss hormone. 

But here’s the good news…

It’s called berberine.

And if it sounds familiar, that’s because it’s rising in popularity as a top supplement for supporting weight loss, metabolic health, and healthy blood sugar.

You may have heard of the synthetic version of this hormone, which has become a popular fad for celebrities looking to lose weight.

But this treatment can be costly, painful, and risky (especially if you’re over the age of 65!)

Thanks to a 2023 review of studies, we now know you can support your body’s production of GLP-1 naturally with berberine!

Researchers discovered that inducing the secretion of GLP-1 with berberine helped prevent mitochondrial damage, reduced adipose tissue fat, and reduced oxidative stress!

The authors even acknowledged the growing popularity of riskier treatments for weight loss, saying…

“...The lower costs of berberine, and its limited side effects and higher availability, make it a promising supplementary [treatment]…”

So if you’ve been feeling hopeless about shedding that unwanted weight you’ve been carrying around for years… 

You’re over the age of 40… 

You often crave sugar and carbs… 

And you typically feel hungry again shortly after eating…

Chances are, activating your GLP-1 hormone with berberine could work for you!

In fact…

“I have in the last couple of days noticed a reduced craving for sweets and the need for snacking in the afternoon.”

Mary M. on 09/24

“I was pleasantly surprised that it actually works. I’ve lost weight. My appetite is curbed and truly only eat when hungry. Give these a try.”

Stephanie J. on 10/02

“After the first few week, I already feel way more appetite control, and I'm much less hungry. That's a strong sign that my blood sugar is becoming more stable!”

K. on 08/07

Today, clinical studies using berberine show great potential for directly improving weight loss through a variety of pathways, including:

GLP-1 can alter appetite by delaying gastric emptying. This means activating GLP-1 secretion with berberine could help you stay fuller for longer and reduce your overall appetite. 

A 2020 animal study demonstrated that berberine has excellent potential as a metabolism-supporting agent, given its ability to reduce appetite. 

After 3 weeks, subjects showed a reduction in total food intake and body weight. 

In one 12-week study in overweight people, taking 500 mg of berberine three times per day caused about 5 pounds of weight loss, on average. The participants also lost 3.6% of their body fat.

A 2020 review of 12 studies on berberine in combination with other lifestyle changes found it helped significantly decrease waist circumference! Researchers also found a significant reduction in body weight and body mass index (BMI.)

Research shows that berberine can block the enzyme that turns complex carbohydrates into simple sugars in the body. 

This means less absorption of carbohydrates and calories from your meals! 

Berberine helps activate an enzyme called AMPK (adenosine monophosphate-activated protein kinase), which is known as “the guardian of metabolism” because it plays a key role in regulating metabolism.

Research in vitro has shown that berberine can inhibit the differentiation of preadipocytes into mature adipocytes (fat cells). This means that berberine may prevent the formation of new fat cells. 

A study published found that berberine may work by effectively blocking the development of new fat cells by downregulating key proteins involved in adipogenesis, the process by which new fat cells are formed.

In a 2008 study of 116 people with imbalanced blood sugar, taking 1 gram of berberine per day for three months lowered fasting blood sugar by 20%.

It also improved levels of blood lipids such as cholesterol and triglycerides.

According to a review of 14 studies, berberine may be as effective as certain blood sugar-regulating alternatives on the market.

“With dozens of studies as validation, berberine truly is one of nature's most impressive remedies for burning belly fat and balancing blood sugar... As long as you’re using its most potent sources – and you’re using it daily.”

Hi, my name is Dr. Chad Walding, Doctor of Physical Therapy and co-founder of NativePath.

The real health crisis we have in America is that our healthcare system is broken.

It doesn’t address or promote healthfulness, it only addresses sickness. 

Even worse – the way it addresses sickness has nothing to do with controllable lifestyle factors – and everything to do with expensive, invasive, unnatural treatments.

For the past decade, I've been battling our conventional “sick care” system on the frontlines by providing natural solutions to my follower's health concerns... 

Leading a health revolution more than 100,000 strong on Facebook...

By now, you should see how supplementing with berberine could be the answer to activating your weight loss hormone and finally improving weight loss, shedding belly fat, balancing blood sugar, promoting long-lasting metabolic health, and so much more… 

In fact, it's a MUST-HAVE for a health-conscious individual like yourself...

Because believe it or not, you deserve to live your golden years to the fullest – free from the worry of weight gain, fatigue, and worsening blood sugar issues in older age…

The reality is this: 

You’ve seen the science behind berberine… 

And how it can help induce your GLP-1 hormone that’s crucial for anyone trying to lose weight. 

But like any other scientifically-backed weight loss ingredient, not all berberine treatments are created equally. 

If you’re interested in trying berberine to reach your goal weight… 

Look for a berberine supplement that contains the highest-quality berberine, berberine HCI (hydrochloride).

We recommend 500mg of berberine daily for effective weight loss support.

Many people experience digestive distress from berberine supplements because they contain fillers and unnecessary additives. Make sure your supplement is from a reputable brand and third-party tested for contaminants. 

That's why at NativePath, we’ve worked tirelessly to find the most potent berberine blend for fast, effective, and natural activation of your GLP-1 hormone. 

We found 500mg of Berberine HCL to be the ideal amount to help switch on your weight loss hormone and support your goals. 

This berberine was then meticulously selected with the highest standard of purity and excellence to provide a berberine-supporting supplement that is as close to nature as possible.

Every serving of Native Berberine contains 500 mg of Berberine (as berberine HCl) to help activate the weight loss hormone GLP-1, as well as our master metabolic switch, the AMPK enzyme.

By supporting these two natural pathways, Native Berberine can help support:

• Weight loss
• Minimized belly fat
• Metabolic health
• Minimized appetite 
• Blood sugar regulation

Plus - it’s 100% free of artificial ingredients, preservatives, binders and also non-GMO.

It’s made with global ingredients in a Good Manufacturing Practice (GMP) certified facility in the USA.

And then third-party tested to ensure purity and potency.

So unlike most weight loss supplements on the market, you can be confident that Native Berberine is effective and safe.

Plus - every order comes with a 365 day money back guarantee, so if you aren’t satisfied, we’ll give you a full refund.

But that just wasn’t good enough…

Because the weight loss industry is saturated with so many ineffective products… 

We wanted to do everything we can to guarantee Native Berberine will provide you the results you’re looking for. 

That’s why…

We believe living vibrantly is your birthright.

It is our mission to help making nature’s best ingredients more accessible through our supplements.

That’s why we formulated Native Berberine as a 3-in-1 formula. 

Every serving contains 500mg of Berberine HCL, along with chromium and bitter melon, two additional ingredients for complete blood sugar support.

We also go the extra mile to ensure that every ingredient we use is backed by science.

An effective 3-in-1 formulation for weight loss goals

Try it risk-free for a whole year

For reduced cravings & healthy cholesterol

No artificial ingredients, corn, soy, sugar, or vegetable oils

We believe Native Berberine to be the most important supplement you can take to lose unwanted weight, maintain metabolic health, and promote healthy blood sugar at any age.

Because Native Berberine:

• Contains 500 mg of Berberine (as berberine HCl) – Berberine’s properties can help activate the weight loss hormone, GLP-1, which can support reduced appetite, body fat, and total weight.
• Contains 400 mg of Chromium (as chromium picolinate) – Helps the body support healthy blood sugar levels by improving insulin sensitivity. It supports healthy metabolism of carbohydrates, fats, and proteins, which may also help maintain healthy glucose levels. 
• Contains 100 mg of Bitter Melon Extract – Derived from the bitter melon fruit (Momordica charantia) , this has traditionally been used to support healthy blood sugar levels. It contains compounds that may help improve glucose metabolism by mimicking insulin and enhancing its effects in the body. 
• Helps naturally activate GLP-1 – The body's GLP-1 hormone naturally declines with age, making losing weight an uphill battle. Studies show supplementing with berberine can help "switch on" your GLP-1 hormone and support weight loss goals. 

• Contains ZERO junk. It’s 100% free of artificial ingredients, preservatives, binders and also non-GMO.
• Is made in a Good Manufacturing Practice (GMP) certified facility in the USA. Native Berberine is 3rd party tested to ensure purity and potency.
• Great value and no-risk. You can experience the NativePath difference for as low as $20 per bottle! Meaning you’ll keep more of your hard earned dollars. What’s more, it’s 100% risk-free. When you place your order today, you’ll have a full 365 days to experience the wide array of metabolic benefits. And if you aren’t THRILLED with the results, we’ll happily help make things right – no questions asked.

That’s exactly what you can expect with NativePath products like Native Berberine.

Just imagine what life would be like if you were able to melt off pounds of unwanted fat without having to take on any risks involved with dramatic treatment decisions…

Getting slimmer around your waistline… 

Looking in the mirror and noticing that your midsection is getting flatter…

No more blood sugar “rollercoaster” overriding your energy during the day… 

Feeling confident about your blood sugar readings…

Ditching your “carb-phobia”...

All of this is possible, and thousands of older adults are already experiencing life-changing results just by adding berberine to their routine. 

While many berberine supplements contain only one ingredient, Native Berberine contains 3 of nature's most potent weight loss supporting ingredients – Berberine, chromium, and bitter melon.

Not only this, but Native Berberine contains these key ingredients in key amounts.

A common practice with some supplement providers is to “fairy dust” – providing the right ingredients, but in insignificant amounts that won’t really make a difference. 

Why would they do this? In some cases, unfortunately, it may be to deceive you – you read the studies, and you know the ingredients are effective for blood sugar support, but they’re hoping you don’t know how much you should take daily…

Here at NativePath, we take great pride in providing not only clean, high-quality ingredients but providing key ingredients in effective amounts so they deliver on their promise.

That’s why we’ve included all 3 of these weight loss supporting ingredients at the proper doses in our premium Native Berberine formula. 

Thus, our 3-in-1 formula may offer 3X the benefits compared to other products.

Sourcing these high-grade ingredients has its challenges. 

The tedious and expensive extraction and dehydration process of berberine can add weeks (sometimes months) to manufacturing processes.

Plus, berberine products that undergo research or third-party testing for quality assurance will be more expensive to source. You’re paying for quality.

To make matters worse… Inflation has caused massive spikes in freight costs, fuel, and in shipping…

On top of that…

Of course, this is a good problem to have, but…

The expected increases in order volume will likely put an even BIGGER strain on production.

As a result, there’s no telling how long we’ll be able to keep this offer available. 

Lucky for you, we set aside a private supply for new customers to offer a special deal. 

Since we know how much you care about your health, you are getting access to our best discount on Native Berberine. 

Where you can stock up on Native Berberine for as low as $20 per bottle.

That’s a whopping 59% OFF!

We’ll even pick up the shipping cost.

That’s right… You get FREE shipping on today’s order – plus a FREE bonus gift!

Of course, you have a full 365 days to try Native Berberine, and if you are not completely satisfied, you can reach out to our friendly team for assistance.

Zero risk, zero hassle – complete convenience. That’s how we do business.

This is incredible news since myself along with many experts believe the berberine to be mission critical for improving weight loss and metabolic health as you age. 

★★★★★

“I have been using this product for a little over a month, and the results are great! In fact, I have dropped pounds...also, sugar levels are dropping.”

S.G. on 05/20

★★★★★

“I was hesitant at first, but so glad that I tried. My blood sugar improved, and I dropped pounds.”

R.R. on 05/04

★★★★★

“I have been taking it for three weeks, and I see a dramatic reduction in blood sugar spikes after I eat. I no longer have those energy crashes shortly after I eat. I have more energy which allows me to be more active, and as a result have lost weight. I would highly recommend this product for anyone who wants to achieve healthy blood sugar levels.”

Angela L. on 04/26

★★★★★

“Helps balance blood sugar immediately. Definitely recommend to everyone.”

Beth B. on 09/23

Customer results have not been independently verified. Individual results may vary.

Thanks to the unique properties found in berberine, it helps activates the GLP-1 hormone – which in turn, helps improve weight loss and support healthy blood sugar.

In fact, studies have found that supplementing with berberine led to significant reductions in body weight, body mass index, and belly fat*. 

Better yet… Taking 500mg of berberine 3 times daily also helped folks lose a shocking 3.6% of their body fat*.

Bottom line: supplementing with berberine can be incredibly helpful for losing stubborn weight and combatting blood sugar imbalances – provided it’s taken consistently.

In order to maintain the metabolic benefits, it’s best to take berberine daily. 

That’s why we created our 3-in-1 Native Berberine formula to make supplementing with berberine easier and more effective than ever. 

So, it makes sense why so many people who have already experienced the benefits of berberine are waiting for our Native Berberine offer to place large orders…

The metabolic benefits of berberine can be experienced with consistent daily use. 

Once you experience the benefits, you won’t want to go a day without it. 

But I’d like to set realistic expectations with you:

Berberine is no “miracle” supplement…

• Take it daily. If you want the best results, don’t skip days!
• Take the proper dose. Using multiple servings daily can help provide metabolic support. 
• Take it for the proper amount of time. Be realistic: results are not going to happen overnight. You’ll need to be consistent if you want to experience metabolic improvements. 
• Take action. Native Berberine is not a quick fix. Other lifestyle changes, such as cutting out ultra-processed foods and moving more daily, will complement the metabolic benefits of berberine and help you achieve your goals faster. Eating, moving, and living better is what being on The Path to better health is all about. 

In other words, Native Berberine isn’t a “magic bullet” against unwanted weight or blood sugar problems.

If you want to experience the full benefits, you must also commit to eating, moving, and living better.

Fortunately, Native Berberine can assist you in doing just that.

But it’s important that you take it consistently for best results. 

Which is why I recommend my clients to:

• Start with at least 6 bottles of Native Berberine at a time.
• And 12 bottles if they want to be completely safe.
• Then take it for a period of at least 60 days (stay consistent!)

And there’s never been a better time to secure your supply of Native Berberine than now…

Right now, when you take advantage of our 12-bottle package of Native Berberine…

Not only will you lock in our special pricing of $20 per bottle...

But you will also receive FREE shipping and a FREE gift! 

You will also secure our biggest discount online and receive the perfect supply needed to experience full results. 

That means you can enjoy the weight loss support and blood sugar-balancing benefits of Native Berberine without ever worrying about running out early. 

But, I do have to mention…

This special price is first come, first serve… Once you leave this page, we can not guarantee that you will see this discount again.

Listen: I’ve given you up to 59% OFF discount for a few reasons…

Firstly, in today’s economy, I understand it can be a struggle to make ends meet… Especially for those on a fixed income.

You shouldn’t have to choose between paying your electric bill or taking care of your health.

Besides, this small investment in your health today could end up saving you thousands of dollars on future medical bills.

The bottom line is that I don’t want money to ever come between you and your health or your weight loss goals.

Secondly, because we are so confident in this product's benefits, we are offering our best-ever price to a limited number of loyal NativePath followers.

Which is exactly why with our exclusive offer, we’re letting you stock up on Native Berberine for as low as just $20 per bottle.

This is the absolute best price we can afford to sell Native Berberine for – and unfortunately, we can not offer this incredible deal for long.

This special sale will only be available for a limited time.

After the seasonal sale ends, Native Berberine will only be available at the full retail price of $49 per bottle.

Best of all, there's no risk involved since our 365-day money back guarantee has you covered for a full year.

This is a no-brainer if you ask me.

All that's left is for you to come and join us. 

So, if you’re ready to experience the NativePath difference yourself… And finally, get on The Path…

Here’s what’s going to happen next:

When you click on the button below, you'll be able to select your desired amount of Native Berberine. 

From there, you can proceed to our safe and secure checkout page, where you can complete your order.

And even better…

At NativePath, we believe in the quality of our products, which is why we offer a Risk-Free 365-Day guarantee.

And when it comes to improving metabolic health, we believe Native Berberine to be the most superior formula to do just that.

But don’t take our word for it…

Countless studies show that supplementing with berberine can provide metabolic benefits such as supporting weight loss and promoting healthy blood sugar.

And while we believe the research speaks for itself – we still want you to feel safe and secure with your purchase. 

That’s why if for any reason you are not completely satisfied with your results, simply reach out to our friendly Customer Care Center for assistance. 

Rest assured, you can order with confidence in knowing that your purchase is backed by our 365-Day Risk Guarantee.

Are you ready to get started?

Because your order of Native Berberine will arrive right to your doorstep.

Then... get ready.

Because as you eagerly rip it open like a kid on Christmas...

I want you to take a serving… Then relax, and kick your feet up...

Because you've just done the most IMPORTANT thing you could do for your metabolic health for the rest of the day.

And within as early as your first few weeks...

Don't be surprised if you wake up with a slight smirk because, for the first time in decades, you actually feel GREAT...

And you’re feeling more confident in your body than ever…

In fact, with each passing week… Your clothes will start fitting more loosely.

The fatigue and cloudy thinking that normally puts a damper on your morning are lifted...

Your energy levels feel normal… 

And you’re finally starting to look and feel like your younger self again…

More importantly...

Finally enjoying quality time with loved ones without your health concerns getting in the way...

All of this - and MORE - is waiting for you when you grab Native Berberine today for as low as 59% OFF.

The one catch?

We are only offering this special discount for a limited time. 

Not to mention, we’ve already sold out of Native Berberine once this year, and it could very well happen again!

So if you're reading this, the good news is we still have enough in stock to offer up to 59% OFF discount...

Which means NOW is the time to take action.

All that's left is for you to get on The Path. 

Click the button below now:

(No monthly subscription. No strings attached.)

Thank you for your time today. 

Dr. Chad Walding

Co-Founder, NativePath

PS. If you're still here, you might have some questions:

Q: What makes Native Berberine different from other supplements on the market?

Many berberine supplements use inferior forms of berberine that are not scientifically studied.

Native Berberine contains the scientifically studied form, berberine HCL, which has been shown in research to promote metabolic health, healthy blood sugar, and weight loss. 

We also include chromium and bitter melon for additional blood sugar support.

In this way, Native Berberine is truly a 3-in-1 formula for long-lasting metabolic health.

Q: How much should I order?

Our best value quantity is our 12-bottle package, which is unbeatable at just $20 per bottle.

Plus, with a 12-bottle supply, you will have more than enough Native Berberine to use continuously every day without worrying about running out.

The 12-bottle package is perfect for folks who are serious about improving their metabolic health, managing blood sugar and supporting their weight loss goals.

Q: How many servings are in each bottle?

Each bottle of Native Berberine contains 30 servings.

Q: What is the best way to use this product?

Simply take 1-2 servings per day. 

Q: How long do I have to use this product before I see results?

Some customers have said that they noticed results in as little as their first week. 

However, more prominent results can be experienced with longer use of berberine. For this reason, it’s smart to stock up on a larger supply of Native Berberine so you can experience the full metabolism-boosting benefits without the risk of running out. 

Q: How will this product be shipped to me, and how quickly?

You can expect to receive your orders within 5-7 business days.

Q: Is it really safe to order this product from this online website?

Yes. Our website is protected by Trust-Guard, an online PCI Compliant Security Scanner software that prohibits security holes from compromising your shopping experience. The Security-Scanned seal is intended to inform shoppers that our business is certified and trusted as safe, responsible, and totally awesome.

Q: What if this product doesn’t work for me?

Many individuals who’ve used berberine see and feel a difference shortly after adding it into their daily routine. However, we want to make sure there’s absolutely no risk involved when it comes to investing in any of our NativePath products.

That’s why you can try Native Berberine for an entire 365 days and if for any reason you're not completely satisfied, simply contact our Customer Care team to begin the return process. Rest assured, you can complete your order today knowing that you're protected by our risk-free 365-day money-back guarantee.

Q: Can I get this product on Amazon?

No. Native Berberine is only available through this exclusive website.

Q: How long will this offer last?

There’s a real chance Native Berberine might run out of stock again. Our offer will likely not last long, and it can be deactivated without notice at any time. So, if you’re even a little curious about what Native Berberine can do for you, now is the best time to stock up and save big while it’s available at our lowest-ever online price.

Simply choose your quantity below by clicking the orange button below.

Go ahead and order your 12, 6, 3, or 1-bottle supply of Native Berberine by choosing one of the packages you see below.

Our twelve-bottle package is by far our best bargain.

Since you need to use this product for at least 60-90 days to experience significant weight loss benefits, we are offering our best deal to those who are most committed to experiencing the biggest results.

The 12-bottle package allows you to save 59% – that means you’ll be locking in the perfect supply for full results at our absolute best possible price of just $0.33/serving.

You’ll also get FREE SHIPPING & a FREE GIFT on this order.

Once folks begin using berberine and experience the difference in the way their body looks and feels, they never want to be without the breakthrough. 

That’s why they typically grab a multi-bottle supply, that way they have more than enough to continue using daily while securing our absolute best price. 

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https://pmc.ncbi.nlm.nih.gov/articles/PMC4167985/#:~:text=GLP%2D1%20neurons%20of%20the%20NTS%20detect%20satiation,activation%20promotes%20satiation%20and%20reduces%20food%20reward.&text=However%2C%20as%20described%20above%2C%20GLP%2D1%20action%20in,the%20satiation%20response%20to%20gastrointestinal%20nutrients%20[42]

https://www.sciencedirect.com/science/article/abs/pii/S0944711312001870

https://pubmed.ncbi.nlm.nih.gov/32690176/

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https://www.nature.com/articles/nrm.2017.95

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1148611/full

https://pmc.ncbi.nlm.nih.gov/articles/PMC3310165/

https://pubmed.ncbi.nlm.nih.gov/30519065/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10376565/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3478874/

https://www.sciencedirect.com/science/article/abs/pii/S0944711312001870

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